GAMBARAN PERUBAHAN HEMODINAMIK PADA PASIEN DENGAN ANESTESI INHALASI DESFLURAN DI INSTALASI BEDAH SENTRAL RSUP FATMAWATI JAKARTA EKA CAHYA NUGRAHA Fakultas Kesehatan Program Studi D IV Keperawatan Anestesiologi Institut Teknologi Dan Kesehatan Bali ABSTRAK Latar Belakang. Anestesi umum merupakan suatu tindakan yang bertujuan menghilangkan nyeri, membuat tidak sadar dan menyebabkan amnesia yang bersifat reversible dan dapat diprediksi. Anestesi umum menyebabkan hilangnya ingatan saat dilakukan pembiusan dan operasi sehingga saat pasien sadar pasien tidak mengingat peristiwa pembedahan yang dilakukan. Anestesi umum inhalasi masih banyak digunakan saat ini karena kemudahan dalam pemberiannya yaitu secara inhalasi. Salah satu obat anestesi inhalasi yaitu desflurane. Tujuan. Mengatahui gambaran perubahan hemodinamik pada pasien dengan anestesi inhalasi desfluran di Intstalasi Bedah Sentral Rumah Sakit Umum Pusat Fatmawati Jakarta. Metode. Desain penelitian ini merupakan deskriptif, dengan pendekatan time series yang dilaksanakan pada tanggal 09 Februari – 13 April 2022. Populasi pada penelitian ini adalah pasien dengan anestesi inhalasi desfluran dengan jumlah sebanyak 78 responden. Teknik sampling yang digunakan adalah non probability sampling dengan teknik purposive sampling. Alat pengumpulan data yang digunakan berupa lembar observasi. Hasil. Berdasarkan jenis kelamin, sebagian besar sample berjenis kelamin perempuan dengan persentase 62,8%. Berdasarkan status fisiknya data didominasi dengan status fisik ASA (American Society of Anesthesiology) 2 dengan persentase 96,2%. Perubahan tekanan darah sistolik pada pasien anestesi inhalasi desflurane pada menit ke 5, 10 dan 15 masing-masing didapatkan penurunan sebesar 17,08%, 18,83% dan 20,08%. Perubahan tekanan darah diastolik pada pasien anestesi inhalasi desflurane pada menit ke 5, 10, dan 15 masing-masing didapatkan penurunan sebesar 18,38%, 19,40% dan 19,69%. Perubahan mean arterial pressure pada pasien anestesi inhalasi desflurane pada menit ke 5, 10 dan 15 masing-masing didapatkan penurunan sebesar 15,96%, 16,49% dan 18,71%. Perubahan heart rate pada pasien anestesi inhalasi desfluran pada menit ke 5, 10 dan 15 masing-masing didapatkan penurunan penurunan sebesar 10,54%, 13,41% dan 13,03%. Kesimpulan. Perubahan hemodinamik pada pasien anestesi inhalasi desflurane setiap menitnya mengalami penurunan tetapi masih dalam batas normal. ix Kata Kunci: Hemodinamik, Anestesi Inhalasi, Desfluran

HEMODYNAMIC CHANGES IN PATIENTS WITH DESFLURANE INHALATION ANESTHESIA IN CENTRAL SURGICAL UNIT, FATMAWATI GENERAL HOSPITAL, JAKARTA EKA CAHYA NUGRAHA Faculty of Health Diploma IV of Nursing Anesthesiology Institute of Technology and Health Bali ABSTRACT Background. General anesthesia is an action that aims to relieve pain, render unconsciousness and cause amnesia that is reversible and predictable. General anesthesia causes memory loss during anesthesia and surgery so that when the patient is conscious the patient does not remember the events of the surgery performed. Inhaled general anesthesia is still widely used today because of the ease of administration, which is by inhalation. One of the inhalation anesthetics commonly used is desflurane. Aim. To find out the hemodynamic changes in patients with desflurane inhalation anesthesia at the Central Surgical Unit of Fatmawati General Hospital, Jakarta. Method. This study was a descriptive study with time series approach and carried out on February 09 – April 13, 2022. The population in this study were patients with desflurane inhalation anesthesia; a total of 78 respondents. The sampling technique implemented to select the respondents was non-probability sampling, the purposive sampling technique. The instrument used for data collection was observation sheets. Results. The majority of respondents (62.8%) were female. Based on ASA (American Society of Anesthesiologist) Physical Status Classification System, the majority of respondents (92.6%) were in ASA 2. The systolic blood pressure of the respondents was found decreasing 17.08% at the minute 5; 18.83% at minute 10; and 20.08% at minute 15. The diastolic blood pressure was also found decreasing 18.38% at the minute 5; 19.40% at the minute 10; and 19.69% at the minute 15. The decrease was also found in the mean arterial pressure, in which by minute 5 the MAP was decreasing 15.96%, and continued to decrease by 16.49% at the minute 10; and 18.71% at the minute 15. The heart rate was also found to be decrease 10.54% at the minute 5, 13.41% at the minute 10; and 13.03% at the minute 15. Conclusion. Patients with desflurane inhalation anesthesia experienced hemodynamic changes every minute, however, the changes remain within the normal range. Keywords: Hemodynamic, Inhalation Anesthesia, Desflurane.