Latar Belakang: Penyakit gagal ginjal kronik sangat mempengaruhi kemampuan pribadi dan kualitas hidup penderita. Penderita gagal ginjal kronis yang menjalani hemodialisis didapatkan bahwa kecenderungan yang dialami adalah terjadi penurunan kualitas hidup. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor determinan dari kualitas hidup pasien aggal ginjal kronik di rumah sakit. Metode Penelitian: Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Sampel penelitian sebanyak 207 pasien. Tehnik sampling menggunakan systematic random sampling. Data dikumpulkan menggunakan kuesioner kemudian dilakukan analisis bivariat dan analisis multivariat. Hasil Penelitian: Hasil analisis bivariat didapatkan bahwa pada domain fisik dan mental (umur, pekerjaan, tekanan darah), domain beban penyakit ginjal (umur, tekanan darah), domain efek penyakit (umur, tekanan darah, lama hemodialisis) (p

Background: Chronic renal failure disease greatly affects the personal abilities and quality of life of patients. Patients with chronic renal failure who undergo hemodialysis are found to have a tendency to experience a decrease in quality of life. The purpose of this study was to determine the determinants of the quality of life of chronic renal failure patients in the hospital. Research Methods: This study is an analytic study with a cross sectional approach. The study sample was 207 patients. The sampling technique used systematic random sampling. Data were collected using a questionnaire and then bivariate analysis and multivariate analysis were performed. Research Results: The results of bivariate analysis showed that in the physical and mental domain (age, occupation, blood pressure), kidney disease burden domain (age, blood pressure), disease effect domain (age, blood pressure, length of hemodialysis) (p