Pendahuluan: Pandemi COVID-19 khususnya Varian Omicron telah memberikan dampak yang luas bagi kehidupan manusia terutama pada aspek ekonomi dan kesehatan, termasuk bagi perawat yang bekerja di garda terdepan dan rawan mengalami kecemasan. Penelitian ini bertujuan untuk mengidentifikasi faktorfaktor yang berhubungan dengan kecemasan perawat terhadap varian Omicron COVID-19. Metode:Penelitian ini dilakukan di Kabupaten Bangli Bali, Indonesia. Teknik sampling yang digunakan adalah snowball sampling. Instrumen yang digunakan adalah kuesioner yang diisi oleh responden sendiri melalui Google Forms. Hasil dan Analisis : univariat, bivariat (uji Chi-square), dan multivariat (regresi logistik berganda) dilakukan untuk analisis penelitian ini. Hasil penelitian ini menemukan bahwa 25,7% responden mengalami kecemasan terhadap varian Omicron COVID-19. Persepsi dan kelengkapan Alat Pelindung Diri (APD) berhubungan signifikan dengan kecemasan perawat terhadap varian Omicron COVID-19. Pembahasan dan kesimpulan: Perawat sangat penting memperhatikan dua hal seperti persepsi dan kelengkapan APD untuk mencegah kecemasan berlebihan bagi perawat yang bekerja di garda terdepan melayani pasien umum termasuk pasien COVID-19. Keywords: COVID-19, Kecemasan, Perawat, Indonesia

Introduction : The COVID-19 pandemic, especially the Omicron Variant, has had a broad impact on human life, especially on the economic and health aspects, including for nurses who work at the forefront and are prone to experiencing anxiety. This study aimed to identify factors associated with nurses' anxiety toward the Omicron Variant of COVID-19. Methods: This study was conducted in the Bangli Regency of Bali, Indonesia. The sampling technique used was snowball sampling. The instrument was a questionnaire that was filled out by the respondents themselves through Google Forms. Univariate, bivariate (Chi-square test), and multivariate analyzes (multiple logistic regression) was performed for this research analysis. Result and Analysis: The results of this study found that 25.7% of respondents experienced anxiety toward the Omicron Variant of COVID-19. Perception and completeness of Personal Protective Equipment (PPE) were significantly associated with nurses' anxiety toward the Omicron Variant of COVID-19.Discuss and Conclution: Nurses are very important to pay attention to two things such as the perception and completeness of PPE to prevent excessive anxiety for nurses who work on the front lines to serve general patients including COVID-19 patients. Keywords: COVID-19, Anxiety, Nurses, Indonesia