Latar Belakang : Lansia sering mengalami penurunan fungsi organ dan rentan terhadap osteoarthritis (OA) dan membutuhkan perawatan jangka panjang akibat nyeri. Nyeri OA dapat ditangani dengan terapi farmakologis dan nonfarmakologis (kompres hangat). Tujuan : Mengidentifikasi efektivitas kombinasi terapi farmakologis dan nonfarmakologis pada lansia dengan OA yang memerlukan perawatan jangka panjang. Metode : Desain Penelitian ini multiple case study dengan pendekatan deskriptif kualitatif time series. Data dikumpulkan melalui wawancara, observasi, dan dokumentasi pada lima partisipan lansia, dan dianalisis menggunakan analisis deskriptif kualitatif time series (case analysis dan cross-case analysis). Hasil : Studi kasus menunjukkan bahwa kombinasi terapi farmakologis dan nonfarmakologis (kompres hangat) selama tiga hari mampu menurunkan nyeri OA dibandingkan terapi non-farmakologis saja. Partisipan seperti Ny. D, Ny. A, dan Ny. L yang konsisten menjalani terapi kombinasi mengalami penurunan nyeri lebih cepat. Sebaliknya, Ny. R dan Tn. R yang hanya menggunakan terapi nonfarmakologis menunjukkan penurunan nyeri yang lebih lambat. Kesimpulan : Kombinasi terapi farmakologis dan non-farmakologis (kompres hangat) selama tiga hari, mampu menurunkan nyeri OA. Partisipan yang konsisten menjalani terapi kombinasi mengalami penurunan nyeri lebih cepat. Saran: Diharapkan bagi penderita OA tetap menggunakan kombinasi terapi farmakologis dan non-farmakologis secara teratur untuk membantu mengurangi nyeri osteoartritis. Kata kunci : Nyeri osteoarthritis, Penatalaksanaan, Lansia, Perawatan Jangka Panjang

Background: The elderly frequently experience decreasing organ function and are prone to osteoarthritis (OA), requiring long-term care due to pain. Osteoarthritis pain can be treated with pharmacological and non-pharmacological interventions, such as warm compresses. Purpose: To identify the effectiveness of a combination of pharmacological and non-pharmacological therapies in the elderly with OA requiring long-term care. Method: This study employed multiple case study with descriptive qualitative time series approach. Data were collected through interview, observation and documentation among 5 elderly patients. Data were analysed by using descriptive qualitative time series (case analysis dan cross-case analysis). Result: The case study showed that a combination of pharmaceutical and nonpharmacological therapy (warm compress) for three days effectively reduced OA pain in comparison to non-pharmacological therapy alone. Participants included Mrs. D, Mrs. A, and Mrs. L who regularly underwent combinations therapy experienced faster pain relief. On the other hand, Mrs. R and Mr. R, who only applied non-pharmacological therapy, experienced a slower relief of pain. Conclusion: The combination of pharmaceutical and non-pharmacological interventions (warm compress) for three days effectively decreased OA pain. Participants who regularly receive combination therapy experienced quicker pain relief. Recommendation: OA patients are anticipated to consistently employ a combination of pharmaceutical and non-pharmacological interventions to reduce osteoarthritis pain. Keywords : Osteoarthritis pain, Management, Elderly, Long-term care